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Shuo Huang’s group reports programmable nanopore for identification of ch...Chirality is a fundamental property of nature. Many biologically significant molecules, including amino acids, nucleotides and saccharides, are chiral in nature. Enantiomers, which are chiral isomers with opposite chiral...
You-Xuan Zheng’s group reports the progress in white CP-OLEDsThe study of organic light-emitting diode (OLED) has become the cutting edge in both academia and industrial community. Because of great potentials in areas as 3D displays, circularly polarized OLEDs (CP-OLEDs) have rece...
Shuo Huang’s group reports non-binary nucleic acid-encoded probes for uni...Rapid and sensitive identification of small molecules, nucleic acids and proteins is useful in a wide variety of sensing applications in clinical diagnostics, drug discovery and environment research. It remains a challen...
JACS full paper: Highly Stable Neutral Corrole Radical: Amphoteric Aromati...Organic radicals are open-shell molecules with unpaired electrons, and their single electron-occupied frontier orbitals are extremely susceptible to electron transfer and release, making them suitable in energy transfer ...
Professor Zhen Liu’s group reports a novel method for precise diagnosis o...Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related death worldwide, and its noninvasive biomarker-based early detection can significantly increase the chance of potentially curative treatmen...
Nature Protocols reports an important progress in single-cell analysis by ...Cells are the basic units of the structure and activities of living species, and single cell-based research is the foundation of life science. However, because of the tiny volume of cells, complex microenvironment within...
Shuo Huang’s group reports structural-profiling of low molecular weight (...RNA is a linear polymer composed of four covalently linked ribonucleotides, but its structure exhibits a lot of diversity. Generally, RNA has three levels of structure: primary, secondary and tertiary. The primary struct...
Back-to-back publication in Angew. Chem.: in vitro and in cellular stabili...i-DNA, also known as i-motif, is a fascinating four-stranded structure fromed by cytosine-rich sequence and discovered in 1993 (Figure 1A). More and more researches evidenced the widespread existence of i-DNA-prone seque...
A new technology for cell imaging: Professor Huangxian Ju proposed an elec...Electrochemiluminescence (ECL) integrates the advantages of high sensitivity of chemiluminescence and potential controllability of electrochemistry, and has been widely used in analytical chemistry and clinical medicine....
Angew Chem reports a precise therapeutic method for early-stage cancers pr...Photodynamic therapy (PDT), which uses photosensitizers to generate reactive oxygen species (ROS) under light irradiation to induce apoptosis of cancer cells, is a noninvasive treatment modality for multifarious cancers....
Accessing the Electrochemical Activity of Single Nanoparticles by Eliminat...
The Electrochemical Deuteration with D2O under External-Reductant-Free Con...As the H/D has the greatest isotopic difference, introducing deuterium into pharmaceutical compounds could improve the stability during metabolism with the minimum impact on the medicinal property of original compounds. ...
The Energy-Converting Microrobot for Delivering and Remotely Regulating Di...Biomedical materials have achieved great advances in targeted drug delivery, biological imaging, and cell regeneration/differentiation. Energy-converting materials represents one of the multidisciplinary frontier researc...
Fude Feng’s research group reports GSH-H2O2 co-activatable photodynamic t...Recently, Prof. Fude Feng (School of Chemistry and Chemical Engineering, Nanjing University) and Prof. Shu Wang (Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences) cooperated to develo...

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