题 目：Mechanism-Based Methods Development for Synthesis of Neurologically Active Natural Products 报告人：Professor Timothy R. Newhouse Department of Chemistry Yale University 地 点：南京大学仙林校区化学化工学院H201蒋雯若报告厅 时 间：2016年10月19日（周三）下午 3:00 邀请人：赵劲教授 Tim Newhouse received his B.A. in Chemistry from Colby College in 2005, and received his Ph.D. in 2010 from The Scripps Research Institute where he worked with Prof. Phil S. Baran and Prof. Donna G. Blackmond. During this time he developed a mechanistically-defined method for the amination of indoles and applied it to the synthesis of psychotrimine, psychotetramine, and the kapakahines. After completing postdoctoral studies with Prof. E.J. Corey at Harvard University, where he completed a stereomechanistic analysis of the Kagan titanium-mediated enantioselective sulfoxide synthesis, he began his independent career in 2013. His research focuses on using a mechanism-based approach to the development of transition-metal catalyzed carbon-carbon bond-forming reactions for the purpose of synthesizing neurologically active small molecule natural products. He has recently published on the development of a novel anilide ligand used for allyl-Pd catalysis to dehydrogenate carbonyl compounds. 配位化学国家重点实验室 南京大学化学化工学院 |