王国强，1987年3月生。2009年和2012年分别获河南大学本科和硕士学位，2016年在南京大学化学化工学院获博士学位。2016-2019年在南京大学物理学院从事博士后研究。2019-2020年赴德国柏林工业大学从事博士后研究。2021年起任南京大学副教授。曾获得中国博士后基金，国家自然科学基金委等基金资助。主要从事理论计算驱动反应设计、人工智能辅助的化学合成等方面的研究。基于新的研究范式，取得的研究成果包括：1）理论计算设计了“双路易碱协同均裂B-B键”的活化新模式，并将其应用于一些C-C, C-B等自由基偶联新反应；2）自动化化学反应路径搜索，计算结合实验设计了硼路易斯酸催化不饱和烃选择性加成反应、催化C-H区域选择性硼化反应；3）探索人工智能辅助自动化合成平台发展与“机理+数据”驱动的化学反应设计策略，加速化学空间探索。以第一/共同第一作者及共同通讯作者在JACS, Angew. Chem., Nat. Comm, Chem. Sci., ACS Catal.等国际有重要影响力的学术期刊发表研究论文40篇。

1）计算驱动的化学反应设计，反应机制与有机合成；
       2）人工智能辅助有机合成自动化。

34. X. Su, G. Li, L. He, S. Chen, X. Yang, G. Wang,*  andS. Li* Nickel-Catalyzed, silyl-directed, ortho-borylation of arenes via an unusual Ni(II)/Ni(IV) catalytic cycle Nat. Commun.2024, DOI: 10.1038/s41467-024-51997-0.

33.  Dai, Y. Fu, M. Wei, F. Wang, B. Tian, L. Zhang, G. Wang*,S. Li* and M. Ding* Harnessing Electro-Descriptors for Mechanistic and Predictive Data Analysis of Photocatalytic Organic Reactions. J. Am. Chem. Soc.2024, DOI: 10.1021/jacs.4c03085.

32. Y. Peng, G. Wang,* H. F. T. Klare M. Oestreich* Ring contraction of saturated cyclic amines and skeletal reorganization of acyclic 1amines Angew. Chem. Int. Ed.,2024, DOI:10.1002/anie.202410483

31. Y. Xiao, M. Wei, F. Wu, L. Tang, G. Wang,* and J.-J. Feng* The Divergent Synthesis of Sulfur-Containing Bridged Cyclobutanes by Lewis Acid Catalyzed Formal Cycloadditions of Pyridinium 1,4-Zwitterionic Thiolates and Bicyclobutanes Angew. Chem. Int. Ed.,2024, DOI:10.1002/anie.202408578

30. F. Wu,+ W.-B. Wu,+ Y. Xiao, Z. Li, L. Tang, H.-X. He, X.-C. Yang, J.-J. Wang, Y. Cai, T.-T. Xu, J.-. Tao, G. Wang,* and J.-J. Feng* Zinc-Catalyzed Enantioselective Formal (3+2) Cycloadditions of Bicyclobutanes with Imines: Catalytic Asymmetric Synthesis of Azabicyclo[2.1.1]hexanes and Beyond Angew. Chem. Int. Ed.,2024, DOI: 10.1002/anie.202406548.

29.  J.-J. Wang, L. Tang, Y. Xiao, W.-B. Wu, G. Wang*,J.-J. Feng* "Switching between the [2π+2σ] and Hetero-[4π+2σ] Cycloaddition Reactivity of Bicyclobutanes with Lewis Acid Catalysts Enables the Synthesis of Spirocycles and Bridged Heterocycles"Angew. Chem. Int. Ed.,2024, DOI: 10.1002/anie.202405222.

28. J.-L. Zhou, Y. Xiao, L. He, X.-Y Gao, X.-C. Yang, W.-B. Wu, G. Wang, J. Zhang,* and J.-J. Feng* "Palladium-Catalyzed Ligand-Controlled Switchable Hetero-(5 + 3)/Enantioselective [2σ+2σ] Cycloadditions of Bicyclobutanes with Vinyl Oxiranes" J. Am. Chem. Soc.2024, DOI: 10.1021/jacs.4c01851.

27. J. Cao, L. Gao, G. Wang*, S. Li* "Visible Light Catalyzed Arylsilylation of Alkenes to Construct Silicon-Containing 1,1-Diaryl Moieties" Green Chem.2024, 26, 4785-4791.

26. L. He,⁺  Y. Fu,⁺  S. Hou,⁺ G. Wang*, J. Zhao, Y. Xing, S. Li and J. Ma* "Reaction Condition- and Functional Group-Specific Knowledge Discovery: Data- and Computation-based Analysis on Transition-Metal-Free Transformation of Organoborons"Artificial Intelligence Chemistry2024, 2, 100034.

25. G. Wang,⁺ X. Wu,⁺ B. Xin,⁺ X. Gu, G. Wang, Y. Zhang, J. Zhao, X. Cheng, C. Chen* and J. Ma* "Machine Learning in Unmanned Systems for Chemical Synthesis" Molecules2023, 28, 2232.

24. L. Gao, X. Liang, L. He, G. Li, S. Chen, J. Cao, J. Ma, G. Wang* and S. Li* "Base-mediated C–B bond activation of benzylic boronate for the rapid construction of b-silyl/boryl functionalized 1,1-diarylalkanes from aromatic alkenes" Chem. Sci. 2023, 14, 11881.

23. Y. Xiao, L. Tang, T.-T. Xu, J.-Y.-H. Sheng, Z. Zhou, L. Yue,G. Wang,* M. Oestreich* and J.-J. Feng* "Atom-economic and stereoselective catalytic synthesis of fully substituted enol esters/carbonates of amides in acyclic systems enabled by boron Lewis acid catalysis" Chem. Sci.2023, 14, 5608.

22. G. Li, Z. Li, L. Gao, S. Chen, G. Wang* and S. Li* "Combined molecular dynamics and coordinate driving method for automatically searching complicated reaction pathways" Phys. Chem. Chem. Phys. 2023, 25, 23696.

21. X. Liu, Y. Wang, S. Chen, Q. Jia, 21. G. Wang* and S. Li,* "Direct benzylic polychlorination of (poly)azines with N-chlorosuccinimide" Org. Chem. Front.2023, 10, 3336.

20. S. Jin, Y. Wang, Y. Tang, J.-Y. Wang, T. Xu, J. Pan, S. Zhang, Q. Yuan, A. U. Rahman, J. D. McDonald, G. Wang*, S. Li and G. Li* "Orientational Chirality, its Asymmetric Control and Computational Study" Research 2022, 2022, 0012. 

19. W. Zou, M. Yang, L. He, G. Wang* and S. Li* "Mechanistic insights into the metal-free deoxygenative borylation of ketones and aldehydes with bis(catecholato)diborane" Chem. Eur. J., 2022, e202203526. 
18. P.-W. Long, G. Wang*, H. F. T. Klare, and M. Oestreich* "Silylium-Ion-Promoted Skeletal Reorganization of β-Silylated Cyclopropanes Bearing an Allyl Group at the Silicon Atom Coupled with Intermolecular Formation of a Quaternary Carbon Atom" ACS Catal. 2022, 12, 12310.

17. L. Gao, X. Liu, G. Li, S. Chen, J. Cao, G. Wang* and S. Li* "1,2-Silylpyridylation Reaction of Aryl Alkenes with Silylboronate" Org. Lett. 2022, 24, 5698.

16. W. Zou, L. Gao, J. Cao, Z. Li, G. Li, G. Wang* and S. Li* "Mechanistic Insight into Hydroboration of Imines from Combined Computational and Experimental Studies" Chem. Eur. J. 2022, 28, e202104004.

15. J. Cao, G. Li, G. Wang*, L. Gao and S. Li* "Iodoperfluoroalkylation of unactivated alkenes via pyridine-boryl radical initiated atom-transfer radical addition" Org. Biomol. Chem. 2022, 20, 2857.

14. G. Wang,+ X. Su,+ L. Gao,+ X. Liu, G. Li and S. Li* "Borane-Catalyzed Selective Dihydrosilylation of Terminal Alkynes: Reaction Development and Mechanistic Insight" Chem. Sci. 2021, 12, 10883.

13. H. Chen, M. Yang, G. Wang*, L. Gao, Z. Ni, J. Zou, and S. Li* "B(C₆F₅)₃-Catalyzed Sequential Additions of Terminal Alkynes to para-Substituted Phenols: Selective Construction of Congested Phenol-Substituted Quaternary Carbons" Org. Lett.2021, 23, 5533.

12. L. Gao⁺, H. Zhang⁺, X. Liu, G. Wang,* and S. Li* "Mechanistic insights into the dearomative diborylation of pyrazines: a radical or non-radical process?" Dalton Trans.,2021, 50, 6982.

11. H. Fang⁺, G. Wang,⁺ and M. Oestreich* "Mild reductive rearrangement of oximes and oxime ethers to secondary amines with hydrosilanes catalyzed by B(C₆F₅)₃" Org. Chem. Front.,2021, 8, 3280. 

10. L. Gao,⁺G. Wang,⁺ H. Chen, J. Cao, X. Su, X. Liu, M. Yang, X. Cheng S. Li* "Metal-free reductive coupling of aliphatic aldehydes/ketones with 4-cyanopyridines: expanded scope and mechanistic studies" Org. Chem. Front., 2020, 7, 2744. 

9. Gao,+G. Wang,+ J. Cao, H. Chen, Y. Gu, X. Liu, X. Cheng, J. Ma, and S. Li* "Lewis Acid-Catalyzed Selective Reductive Decarboxylative Pyridylation of N-Hydroxyphthalimide Esters: Synthesis of Congested Pyridine-Substituted Quaternary Carbons" ACS Catal.,2019, 9, 10142.

8. P. Gao,^‡G. Wang^‡, L. Xi, M. Wang, S. Li,* and Z. Shi* "Transition-Metal-Free Defluorosilylation of Fluoroalkenes with Silylboronates" Chin. J. Chem., 2019, 37, 1009.

7. G. Wang^‡, L. Gao^‡, H. Chen, X. Liu, J. Cao, S. Chen, X. Cheng and S. Li* "Borane-Catalyzed Chemoselective Hydroarylation of 1,3-Dienes with Phenols" Angew. Chem. Int. Ed. 2019, 58, 1694.

6. M. Yang⁺, G. Wang^‡, J. Zou and S. Li*, "Mechanistic Insight Into the AuCN Catalyzed Annulation Reaction of Salicylaldehyde and Aryl Acetylene: Cyanide Ion Promoted Umpolung Hydroacylation/Intramolecular Oxa-Michael Addition Mechanism"Front. Chem. 2019, 7, 557. 

5. L. Gao,^‡G. Wang^‡, J. Cao, D. Yuan, X. Cheng, X. Guo, S. Li* "Organocatalytic decarboxylative alkylation of N-hydroxy-phthalimide esters enabled by pyridine-boryl radicals" Chem. Commun., 2018, 54, 11534.

4. J. Cao^‡, G. Wang^‡, L. Gao, X. Cheng and S. Li* "Organocatalytic reductive coupling of aldehydes with 1,1-diarylethylenes using an in situ generated pyridine-boryl radical" Chem. Sci.,2018, 9, 3664.

3. J. Hu^‡, G. Wang^‡, S. Li* and Z. Shi* "Selective C-N Borylation of Alkyl Amines Promoted by Lewis Base" Angew. Chem. Int. Ed. 2018, 57, 15227. 

2. D. Yan^‡, G. Wang^‡, F. Xiong^‡, W. Sun, Z. Shi, Y. Lu,* S. Li* and J. Zhao,* "A selenium-catalysed para-amination of phenols" Nat. Comm. 2018, 9, 4293.

1. G. Wang, J. Cao, L. Gao, W. Chen, W. Huang, X. Cheng* and S. Li* "Metal-Free Synthesis of C-4 Substituted Pyridine Derivatives Using Pyridine-boryl Radicals via a Radical Addition/Coupling Mechanism: A Combined Computational and Experimental Study" J. Am. Chem. Soc. 2017, 139, 3904. 

0. G. Wang, H. Zhang, J. Zhao, W. Li, J. Cao, C. Zhu* and S. Li* "Homolytic Cleavage of a B−B Bond by the Cooperative Catalysis of Two Lewis Bases: Computational Design and Experimental Verification" Angew. Chem. Int. Ed.2016, 55, 5985.

1. 《人工智能与化学》：面向化学、材料、环境科学等专业的本科三、四年级，研究生；秋季学期

2. 《结构化学》：化学拔尖计划本科三年级；春季学期

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