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个人简介
2003年毕业于南京大学化学系,获理学学士学位。同年赴美国匹兹堡大学(University of Pittsburgh),师从 Dennis Curran 教授,2009年获博士学位。2008年至2011年在麻省理工学院(MIT)化学系美国科学院院士 Stephen Buchwald 实验室进行博士后研究。2012年至2017年在哈佛大学医学院(Harvard Medical School)任 Instructor。2017年起在南京大学任副教授、博导,2023年起任教授。以通讯作者发表的期刊包括 Nature Synthesis,Nature Catalysis,Chem,Angew. Chem. Int. Ed.,Cell Rep. Phys. Sci.,Green Chem.,Chem. Sci.,ACS Catal. 等。出版中文专章1部,英文专章1部。申请发明专利5项,授权2项。 课题组网页:https://www.x-mol.com/groups/wangxiao 展示全部
工作经历
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研究方向
1. 流动化学(Flow Chemistry): 利用微通道反应器传质快、传热效率高、安全、废料排放少、易于实现量产等独特优势,开展有利安全生产和环保的原创性工作,解决C1化学、药物合成、助剂合成、燃油脱硫等一系列工业中的实际问题。 2. 前生命化学(Prebiotic Chemistry): 以流动化学等前沿技术为工具,研究生命起源中的重点问题以及仿生合成,并发展绿色化学新理念。 学术成果
前生命化学、仿生合成: (1) Q.-Q. Chen, Z.-R. Zhao, Y. Patehebieke, X. Wang*, Regioselective ribonucleoside synthesis through Ti-catalysed ribosylation of nucleobases, Nat. Synth. 2023, 2, 348–356. (2) Z.-R. Zhao, X. Wang*, A plausible prebiotic selection of ribose for RNA - formation, dynamic isolation, and nucleotide synthesis based on metal-doped clays, Chem 2021, 7, 3292–3308. (3) X. Wang*, Challenges and outlook for catalytic direct amidation reactions, Nat. Catal. 2019, 2, 98–102. (4) Y. Patehebieke, Z.-R. Zhao, S. Wang, H.-X. Xu, Q.-Q. Chen, X. Wang*, Cavitation as a plausible driving force for the prebiotic formation of N9 purine nucleosides, Cell Rep. Phys. Sci. 2021, 2, 100375. (5) Q.-Q. Chen#, H.-X. Xu#, B.-Y. Zhao, Y. Patehebieke, Z.-R. Zhao*, X. Wang*, Rise of β-furanosyl ribonucleosides as the extant RNA component facilitated by simple divalent transition-metal minerals, Sci. China Chem. 2025, DOI: 10.1007/s11426-024-2445-6 (6) H.-X. Xu, Z.-R. Zhao,X. Wang*, A selective non-enzymatic synthesis of ribose simply from formaldehyde, metal salts and clays, Chem. Commun. 2025, 61, 1701–1704. (7) Z.-R. Zhao#, Q.-Q. Chen#, B.-Y. Zhao#, W.-J. Qin, Q. Liu, X. Wang*, A hypothetical pathway of unified ribonucleotide formation on the surface of meteorite phosphide minerals, BioX 2025, DOI: 10.70737/32hvbs52 微反应器、流动化学: (1) H.-X. Xu, Z.-R. Zhao, Y. Patehebieke, Q.-Q. Chen, S.-G. Fu, S.-J. Chang, X.-X. Zhang, Z.-L. Zhang, X. Wang*, Continuous-flow step-economical synthesis of thiuram disulfides via visible-light photocatalytic aerobic oxidation, Green Chem. 2021, 23, 1280–1285. (2) H.-X. Xu, S.-G. Fu, Y.-H. Tao, P.-H. Luo, Z.-Q. Song, Y. Zhang, Z.-L. Zhang, X. Wang*, One-step simultaneous synthesis of an industrially important rubber accelerator and a lubricant additive by disulfide bond contraction, Synlett 2023, 34, 57–62. (3) Z.-R. Zhao, H.-X. Xu, X. Wang*, MoS2-catalyzed aerobic synthesis of tetraethylthiuram disulfide in batch and continuous flow, Synlett 2023, 34, 488–492. (4) X.-J. Li#, H.-X. Xu#, Y.-H. Tao, S.-G. Fu, Z.-L. Zhang, X. Wang*, Zn-Catalyzed sustainable one-pot synthesis of rubber accelerator TMTM and lubricant additive TPPT, ACS Sustain. Chem. Eng. 2024, 12, 15972–15979. (5) Y.-Z. Xue#, X.-J. Li#, Z.-R. Zhao, H.-X. Xu, S.-G. Fu, F.-X. Wang, X. Wang*, A waste-free packed-bed continuous-flow synthesis of disulfiram with a composite catalyst, React. Chem. Eng. 2025, DOI: 10.1039/D5RE00028A (6) S. Wang, Y. Patehebieke, Z. Zhou*, Z.-B. Zhang, X. Wang*, Catalyst-free biphasic oxidation of thiophenes in continuous-flow, J. Flow Chem. 2020, 10, 597–603. (7) X. Wang*, H. Wang*, Y. Sun*, Synthesis of acrylic acid derivatives from CO2 and ethylene, Chem 2017, 3, 211–228. (8) Y. Deng, X. Wei, H. Wang, Y. Sun, T. Noël, X. Wang*, Disulfide-catalyzed visible-light-mediated oxidative cleavage of C=C bonds and evidence of an olefin–disulfide charge-transfer complex, Angew. Chem. Int. Ed. 2017, 56, 832–836. (9) Y. Deng, H. Wang, Y. Sun, X. Wang*, Principles and applications of enantioselective hydroformylation of terminal disubstituted alkenes, ACS Catal. 2015, 5, 6828–6837. (10) N. J. W. Straathof, B. J. P. Tegelbeckers, V. Hessel, X. Wang*, T. Noël*, A mild and fast photocatalytic trifluoromethylation of thiols in batch and continuous-flow, Chem. Sci. 2014, 5, 4768–4773. (11) X. Wang*, G. D. Cuny*, T. Noël*, A mild, one-pot Stadler-Ziegler synthesis of arylsulfides facilitated by photoredox catalysis in batch and continuous-flow, Angew. Chem. Int. Ed. 2013, 52, 7860–7864. 发明专利: (1) 王晓,付顺国,张旭旭,许皓星,王芳晓,杨瑞朝,袁亚楠;一种光催化氧化制备二硫化四烃基秋兰姆的方法,ZL 202011315319.5 (2) 王晓,寿文晖,叶尔森•帕特合别克,王苏,冯奕景,许皓星,赵泽润,陈倩倩,陶玉红;一种大孔弱碱型阴离子树脂负载钨基催化剂及其微通道连续流氧化体系和应用,ZL 202210330011.0 (3) 王晓,许皓星,陶玉红,赵泽润,陈倩倩,寿文晖,李行健,付顺国;一种同时生产橡胶促进剂TMTM和润滑油添加剂TPPT的方法,ZL 202210752161.0 (4) 王晓,赵泽润,许皓星,叶尔森•帕特合别克;一种二硫化钼催化二硫化四乙基秋兰姆的制备方法,ZL 202211125886.3 (5) 王晓,许皓星,陈倩倩,赵泽润,陶玉红;一种液-液连续流微通道制备醛类化合物的方法,CN 202211587204.0 (6) 王晓,顾成成,齐煜,许皓星,陶玉红;一种用于制备微乳液和杂环化合物的微通道反应器,CN 202410401995.6 专著、专章: (1) Homogeneous Photoreactions in Continuous-Flow in Photochemical Processes in Continuous-Flow Reactors: From Engineering Principles to Chemical Reactions, Y. Deng, X. Wang*, World Scientific Press, 2017. (2) 《微界面传质强化技术》:第一章《绪论》,周政,王晓,杨国强;主编:张志炳;化学工业出版社,2020 课程名称、上课时间地点
1. 流动化学导论(3学分,54学时),秋季学期 2. 化学化工行业就业创业指导(1学分,18学时),春季学期 教学大纲、考试要求
教学资源(上课讲义、参考资料等)
课题组风采
https://www.x-mol.com/groups/wangxiao |