冯福德
职务: 博士生导师
联系电话: 025-89682119
办公地址: 化学楼C413
电子邮箱: fengfd@nju.edu.cn
课题组主页:
个人简介
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工作经历

2009年毕业于中国科学院化学研究所,获理学博士学位。2009年至2013年,分别于美国佛罗里达大学和贝勒医学院从事博士后研究工作。2013年入选国家级青年人才计划。2014年起,任南京大学化学化工学院高分子科学与工程系教授、博士生导师。

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研究方向

    1)光敏感材料;2)可激活型光动力学治疗;3)活细胞内的染料分子原位合成。


学术成果

1.Jinlei Peng, Ke Du, Jian Sun, Xianli Yang, Xia Wang, Xiaoran Zhang, Gang Song, Fude Feng*, Photocatalytic Generation of Hydrogen Radical (H) with GSH for Photodynamic Therapy, Angew. Chem. Int. Ed.DOI:10.1002/anie.202214991, accepted.

2.Jian Sun, Xiaoran Zhang, Xia Wang, Jinlei Peng, Gang Song, Yufei Di, Fude Feng* and Shu Wang*, Dithiol-Activated Bioorthogonal Chemistry for Endoplasmic Reticulum-Targeted Synergistic Chemophototherapy, Angew. Chem. Int. Ed.2022, 61, e202213765. https://doi.org/10.1002/anie.202213765(VIP paper)

3.Hao Heng#, Gang Song#, Xuetong Cai, Jian Sun, Ke Du, Xiaoran Zhang, Xia Wang, Fude Feng* and Shu Wang*, Intrinsic Mitochondrial Reactive Oxygen Species (ROS) Activate the In Situ Synthesis of Trimethine Cyanines in Cancer Cells,Angew. Chem. Int. Ed.2022, 61, e202203444. https://doi.org/10.1002/anie.202203444

4.Xuetong Cai; Andi Hu; Fude Feng*. Synthesis of a Sulfonated Methylene Blue-Backboned Polymer for Biodetections, Dyes Pigm. 2022, 203, 110360. 

5.Gang Song#, Hao Heng#, Jiaqi Wang, Ronghua Liu, Yiming Huang, Huan Lu, Ke Du, Fude Feng* and Shu Wang*, Photoactivated in situ Generation of Near Infrared Cyanines for Spatiotemporally Controlled Fluorescence Imaging in Living Cells, Angew. Chem., Int. Ed.202160 (31), 16889-16893. https://doi.org/10.1002/anie.202103706 (Hot paper)

6.Jian Sun, Xuetong Cai, Chengjun Wang, Ke Du, Weijian Chen, Fude Feng* and Shu Wang*, Cascade Reactions by Nitric Oxide and Hydrogen Radical for Anti-Hypoxia Photodynamic Therapy Using an Activatable Photosensitizer, J. Am. Chem. Soc. 2021143, 868–878. https://dx.doi.org/10.1021/jacs.0c10517

7.Xuetong Cai, Luyang Ji, Hao Tang, Rong Wang* and Fude Feng*, One Pot Synthesis and Self-Assembly of Methylene Blue-Backboned Polymers, Chem. Commun. 2021, 57(92), 12313-12316.

8.Jian Sun, Ke Du, Jiajie Diao, Xuetong Cai, Fude Feng* and Shu Wang*, GSH and H2O2 Co-Activatable Mitochondria-Targeted Photodynamic Therapy under Normoxia and Hypoxia, Angew. Chem., Int. Ed.202059, 12122–12128. https://doi.org/10.1002/anie.202003895(VIP paper)

9.Xuewei Wang, Ke Du, Hao Heng, Weijian Chen, Xiao Li, Xiaoxuan Wei, Fude Feng* and Shu Wang*, Precise engineering of apoferritin through site-specific host–guest binding, Chem. Commun. 2020, 56, 12897–12900.

10.Ke Du, Qiuyu Xia, Hao Heng, and Fude Feng*, Temozolomide–Doxorubicin Conjugate as a Double Intercalating Agent and Delivery by Apoferritin for Glioblastoma Chemotherapy, ACS Appl. Mater. Interfaces2020, 12(31), 34599–34609.

11.Weijian Chen, Shuyi Li, Xiao Li, Chi Zhang, Xiantao Hu, Fan Zhu, Guosong Shen and Fude Feng*, Iron sulfur clusters in protein nanocages for photocatalytic hydrogen generation in acidic aqueous solutions, Chem. Sci.201910, 2179−2185.

12.Xiao Li, Fenli Shao, Jian Sun, Ke Du, Yang Sun, Fude Feng*, Enhanced CopperTemozolomide Interactions by Protein for Chemotherapy against Glioblastoma Multiforme, ACS Appl. Mater. Interfaces2019, 11, 41935−41945.

13.Jian Sun, Xiao Li, Jia Cao, Qi Sun, Yajie Zhang, Xuewei Wang, Tiantian Wu, Xiantao Hu, and Fude Feng*, Mitochondria Targeting Fluorescent Probes Based on Through Bond Energy Transfer for Mutually Imaging Signaling Molecules H2S and H2O2Chem. Eur. J. 201925, 9164−9169.

14.Xiantao Hu, Weijian Chen, Shuyi Li, Jian Sun, Ke Du, Qiuyu Xia, and Fude Feng*, Diiron Dithiolate Complex Induced Helical Structure of Histone and Application in Photochemical Hydrogen Generation, ACS Appl. Mater. Interfaces201911, 19691−19699.

15.Weijian Chen, Xuetong Cai, Luyang Ji, Xiao Li, Xuewei Wang, Xiaoran Zhang, Yajing Gao, Fude Feng*, A Photosynthesis-Inspired Supramolecular System: Caging Photosensitizer and Photocatalyst in Apoferritin, Photosynth. Res.2019, 142, 169−180.

16.Jinkai Ji, Tiantian Wu, Yajie Zhang and Fude Feng*, Light-Controlled in Vitro Gene Delivery Using Polymer-Tethered Spiropyran as a Photoswitchable Photosensitizer, ACS Appl. Mater. Interfaces201911, 15222−15232.

17.Jinkai Ji, Xiao Li, Tiantian Wu, and Fude Feng*, Spiropyran in Nanoassemblies as a Photosensitizer for Photoswitchable ROS Generation in Living Cells, Chem. Sci. 20189, 5816−5821.

18.Jian Sun, Xiao Li, Ke Du and Fude Feng*, A water soluble donor–acceptor–donor conjugated oligomer as a photosensitizer for mitochondria-targeted photodynamic therapy, Chem. Commun.2018, 54, 9194−9197.

19.Xuewei Wang, Chi Zhang, Yajie Zhang, Jian Sun, Leilei Cao, Jinkai Ji, and Fude Feng*, Facile Crosslinking of Polythiophenes by Polyethylenimine via Ester Aminolysis for Selective Cu(II) Detection in Water, Biosens. Bioelectron. 2018109, 255−262.

20.Xiao Li, Yajie Zhang, Jian Sun, Weijian Chen, Xuewei Wang, Fenli Shao, Yuyu Zhu, Fude Feng*, and Yang Sun*, Protein Nanocage-Based Photo-Controlled Nitric Oxide Releasing Platform, ACS Appl. Mater. Interfaces 20179, 19519−19524.

21.Yajie Zhang, Xiao Li, Tiantian Wu, Jian Sun, Xuewei Wang, Leilei Cao, and Fude Feng*, Cationic Polythiophenes as Gene Delivery Enhancer, ACS Appl. Mater. Interfaces20179, 16735−16740.

课程名称、上课时间地点

1. 一年级本科生课程:大学化学实验

2. 一年级研究生课程:现代高分子化学


教学大纲、考试要求
教学资源(上课讲义、参考资料等)
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